世联博研,世联博研(北京)科技有限公司—专注生物力学和3D生物打印服务等再生医学服务

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产品编号	产品名称	产地	价格/规格
BioTester	an investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets strain effects on collagen proteolysis in heart valve tissues comparison of biomechanical properties and microstructure of trabeculae carneae, papillary muscles, and myocardium in the human heart rate-dependency of the mechanical behavior of semilunar heart valves under biaxial deformation an investigation of layer-specific tissue biomechanics of porcine atrioventricular valve anterior leaflets the degradation and performance of electrospun supramolecular vascular scaffolds examined upon in vitro enzymatic exposure mechanical damage characterization in human femoropopliteal arteries of different ages cyclic strain affects macrophage cytokine secretion and extracellular matrix turnover in electrospun scaffolds image-based analysis of uniaxial ring test for mechanical characterization of soft materials and biological tissues mechanical properties of autologous pericardium change with fixation time: implications for valve reconstruction tissue level mechanical properties and extracellular matrix investigation of the bovine jugular venous valve tissue regional biaxial mechanical data of the mitral and tricuspid valve anterior leaflets mechanics of the tricuspid valve-from clinical diagnosis/treatment, in-vivo and in-vitro investigations, to patient-specific biomechanical modeling. an investigation of the glycosaminoglycan contribution to biaxial mechanical behaviours of porcine atrioventricular heart valve leaflets macrophage-driven biomaterial degradation depends on scaffold microarchitecture the effect of axial torsion on the mechanical properties of the annulus fibrosus integration of polarized spatial frequency domain imaging (psfdi) with a biaxial mechanical testing system for dynamic quantification of collagen architecture in soft collagenous tissues an integrated opto-mechanical system for quantification of dynamic microstructure and mechanics of heart valve tissues effects of longitudinal pre-stretch on the mechanics of human aorta before and after thoracic endovascular aortic repair (tevar) in trauma patients human in vitro model of material-driven vascular regeneration reveals how cyclic stretch and shear stress differentially modulate inflammation and tissue formation some effects of different constitutive laws on fsi simulation for the mitral valve biomechanical restoration potential of pentagalloyl glucose after arterial extracellular matrix degeneration an investigation of the effect of freezing storage on the biaxial mechanical properties of excised porcine tricuspid valve anterior leaflets a detailed mechanical and microstructural analysis of the ovine tricuspid valve leaflets the regional-dependent biaxial behavior of young and aged mouse skin: a detailed histomechanical characterization, residual strain analysis, and constitutive model biaxial mechanical behavior of bovine saphenous venous valve leaflets prevalence of calcification in human femoropopliteal arteries and its association with demographics, risk factors, and arterial stiffness comparison of corneal biomechanics after myopic small-incision lenticule extraction compared to lasik: an ex vivo study dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: case report and failure analysis puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization biomechanical evaluation of a personalized external aortic root support applied in the ross procedure polydopamine as sizing on carbon fiber surfaces for enhancement of epoxy laminated composites comparison of in vivo vs. ex situ obtained material properties of sheep common carotid artery soy protein/cellulose nanofiber scaffolds mimicking skin extracellular matrix for enhanced wound healing new findings confirm the viscoelastic behaviour of the inter-lamellar matrix of the disc annulus fibrosus in radial and circumferential directions of loading 3d printed, controlled release, tritherapeutic tablet matrix for advanced anti-hiv-1 drug delivery computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model pressure-induced end-plate fracture in the porcine spine: is the annulus fibrosus susceptible to damage? dual electrospun supramolecular polymer systems for selective cell migration regional mechanical and biochemical properties of the porcine cortical meninges new insights into the viscoelastic and failure mechanical properties of the elastic fiber network of the inter-lamellar matrix in the annulus fibrosus of the disc initial scaffold thickness affects the emergence of a geometrical and mechanical equilibrium in engineered cardiovascular tissues development of an improved parameter fitting method for planar biaxial testing using rakes the biomechanics of the inter-lamellar matrix and the lamellae during progression to lumbar disc herniation: which is the weakest structure? mechanically robust cryogels with injectability and bioprinting supportability for adipose tissue engineering biomechanical characterization of human dura mater 3d printed, pva–paa hydrogel loaded-polycaprolactone scaffold for the delivery of hydrophilic in-situ formed sodium indomethacin a transverse isotropic constitutive model for the aortic valve tissue incorporating rate-dependency and fibre dispersion: application to biaxial deformation decoupling the effect of shear stress and stretch on tissue growth and remodeling in a vascular graft an investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves biaxial mechanical data of porcine atrioventricular valve leaflets biaxial mechanical characterization of atrioventricular heart valves biaxial experimental and analytical characterization of a dielectric elastomer biaxial mechanical properties of bovine jugular venous valve leaflet tissues comparison of femoropopliteal artery stents under axial and radial compression, axial tension, bending, and torsion deformations constitutive modeling of human femoropopliteal artery biaxial stiffening due to aging and diabetes constitutive modeling of jugular vein-derived venous valve leaflet tissues design and characterization of a hyperelastic tubular soft composite in situ heart valve tissue engineering using a bioresorbable elastomeric implant – from material design to 12 months follow-up in sheep jetvalve: rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery mechanically robust electrospun hydrogel scaffolds crosslinked via supramolecular interactions nondestructive mechanical characterization of developing biological tissues using inflation testing on the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture paraspinal muscle passive stiffness remodels in direct response to spine stiffness: a study using the ent1-deficient mouse tensile behaviour of individual fibre bundles in the human lumbar anulus fibrosus urinary bladder versus gastrointestinal tissue: a comparative study of their biomechanical properties for urinary tract reconstruction a comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosis tensile properties acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro age-dependent changes in geometry, tissue composition and mechanical properties of fetal to adult cryopreserved human heart valves are adipose-derived stem cells cultivated in human platelet lysate suitable for heart valve tissue engineering biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region biomechanical characterization of ascending aortic aneurysms biomechanical properties and microstructure of heart chambers: a paired comparison study in an ovine model characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis constitutive description of human femoropopliteal artery aging deposition of a hydrophilic nanocomposite-based coating on a silicone hydrogel through a laser process to minimize uv exposure and bacterial contamination improved geometry of decellularized tissue engineered heart valves to prevent leaflet retraction inflation and bi-axial tensile testing of healthy porcine carotid arteries modulation of collaen fiber orientation by strain-controlled enzymatic degradation nanocomposited coatings produced by laser-assisted process to prevent silicone hydrogels from protein fouling and bacterial contamination patient specific vascular benchtop models for development and validation of medical devices for minimally invasive procedures peak stress in the annulus fibrosis under cyclic biaxial tensile loading phototactic guidance of a tissue-engineered soft-robotic ray planar biaxial testing of heart valve cusp replacement biomaterials: experiments, theory and material constants planar biaxial testing of soft biological tissue using rakes: a critical analysis of protocol and fitting process production of synthetic, para-aramid and biopolymer nanofibers by immersion rotary jet-spinning quantification of coupled stiffness and fiber orientation remodeling in hypertensive rat right-ventricular myocardium using 3d ultrasound speckle tracking with biaxial testing the aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae the choice of a constitutive formulation for modeling limb flexion-induced deformations and stresses in the human femoropopliteal arteries of different ages the effect of local hydration environment on the mechanical properties and unloaded temporal changes of isolated porcine annular samples adipose derived tissue engineered heart valve biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: effects of collagenase concentration and equibiaxial strain state building a better infarct: modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction corneal collagen cross-linking combined with simulation of femtosecond laser-assisted refractive lens extraction: an ex vivo biomechanical effect evaluation development of non-cell adhesive vascular grafts using supramolecular building blocks high-irradiance cxl combined with myopic lasik: flap and residual stroma biomechanical properties studied ex-vivo leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion methods for using 3-d ultrasound speckle tracking in biaxial mechanical testing of biological tissue samples nanocomposite silicone hydrogels with a laser-assisted surface modification for inhibiting the growth of baterial biofilm regional and depth variability of porcine meniscal mechanical properties through biaxial testing superior tissue evolution in slow degrading scaffolds for valvular tissue engineering the biomechanics of eyelid tarsus tissue cardiac function of the naked mole-rat: echophysiological responses to working underground directional biomechanical properties of porcine skin tissue modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues should a native depth-dependent distribution of human meniscus constitutive components be considered in fea-models of the knee joint? strain-dependent modulation of macrophage polarization within scaffolds structural and mechanical adaptations of right ventrical free wall myocardium to pressure overload the biaxial biomechanical behavior of adominal aortic aneurysm tissue the biaxial mechanical behaviour of abdominal aortic aneurysm intraluminal thrombus: classification of morphology and the determination of layer and region specific properties the impact of long term freezing on the mechanical properties of porcine aortic tissue vascular elastography: a validation study a nanocomposite contact lens for the delivery of hydrophilic protein drugs comparison of methods used to measure the thickness of soft tissues and their influence on the evaluation of tensile stress corneal resistance to shear force after uva-riboflavin cross-linking in vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells mechanical analysis of ovine and pediatric pulmonary artery for heart valve stent design mechanics of the pulmonary valve in the aortic position reduction of stromal swelling pressure after uva-riboflavin cross-linking a murine experimental model for the mechanical behavior of viable right-ventricular myocardium an examination of the mechanical properties of the annulus fibrosus: the effect of vibration on the intra-lamellar matrix strength application of simple biomechanical and biochemical tests to heart valve leaflets: implications for heart valve characterization and tissue engineering biomechanical properties of the transverse carpal ligament under biaxial strain multi-scale mechanical characterization of scaffolds for heart valve tissue engineering a comparison of uniaxial and biaxial mechanical properties of the annulus fibrosus: a porcine model does vibration influence the initiation of intervertebral disc herniation novel lap test determines the mechanics of delamination between annular lamellae of the intervertebral disc surfactant assisted incorporation of single-walled carbon nanotubes into a chitosan-polyvinylpyrrolidone polymer an examination of the influence of strain rate on subfailure mechanical properties of the annulus fibrosus biaxial mechanical testing of human sclera effects of sclera stiffness on biomechanics of the optic nerve head in glaucoma effects of sclera stiffness properties on optic nerve head biomechanics fabrication of nanofiber reinforced protein structures for tissue engineering strain uniformity in biaxial specimens is highly sensitive to attachment details the influence of the tensile material properties of single annulus fibrosus lamellae and the interlamellar matrix strength on disc herniation and progression functional arrays of human pluripotent stem cell-derived cardiac microtissues	cellscale	李先生
BioTester	an investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets, strain effects on collagen proteolysis in heart valve tissues, comparison of biomechanical properties and microstructure of trabeculae carneae, papillary muscles, and myocardium in the human heart, rate-dependency of the mechanical behavior of semilunar heart valves under biaxial deformation, an investigation of layer-specific tissue biomechanics of porcine atrioventricular valve anterior leaflets, the degradation and performance of electrospun supramolecular vascular scaffolds examined upon in vitro enzymatic exposure, mechanical damage characterization in human femoropopliteal arteries of different ages, cyclic strain affects macrophage cytokine secretion and extracellular matrix turnover in electrospun scaffolds, image-based analysis of uniaxial ring test for mechanical characterization of soft materials and biological tissues, mechanical properties of autologous pericardium change with fixation time: implications for valve reconstruction, tissue level mechanical properties and extracellular matrix investigation of the bovine jugular venous valve tissue, regional biaxial mechanical data of the mitral and tricuspid valve anterior leaflets, mechanics of the tricuspid valve-from clinical diagnosis/treatment, in-vivo and in-vitro investigations, to patient-specific biomechanical modeling., an investigation of the glycosaminoglycan contribution to biaxial mechanical behaviours of porcine atrioventricular heart valve leaflets, macrophage-driven biomaterial degradation depends on scaffold microarchitecture, the effect of axial torsion on the mechanical properties of the annulus fibrosus, integration of polarized spatial frequency domain imaging (psfdi) with a biaxial mechanical testing system for dynamic quantification of collagen architecture in soft collagenous tissues, an integrated opto-mechanical system for quantification of dynamic microstructure and mechanics of heart valve tissues, effects of longitudinal pre-stretch on the mechanics of human aorta before and after thoracic endovascular aortic repair (tevar) in trauma patients, human in vitro model of material-driven vascular regeneration reveals how cyclic stretch and shear stress differentially modulate inflammation and tissue formation, some effects of different constitutive laws on fsi simulation for the mitral valve, biomechanical restoration potential of pentagalloyl glucose after arterial extracellular matrix degeneration, an investigation of the effect of freezing storage on the biaxial mechanical properties of excised porcine tricuspid valve anterior leaflets, a detailed mechanical and microstructural analysis of the ovine tricuspid valve leaflets, the regional-dependent biaxial behavior of young and aged mouse skin: a detailed histomechanical characterization, residual strain analysis, and constitutive model, biaxial mechanical behavior of bovine saphenous venous valve leaflets, prevalence of calcification in human femoropopliteal arteries and its association with demographics, risk factors, and arterial stiffness, comparison of corneal biomechanics after myopic small-incision lenticule extraction compared to lasik: an ex vivo study, dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: case report and failure analysis, puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization, biomechanical evaluation of a personalized external aortic root support applied in the ross procedure, polydopamine as sizing on carbon fiber surfaces for enhancement of epoxy laminated composites, comparison of in vivo vs. ex situ obtained material properties of sheep common carotid artery, soy protein/cellulose nanofiber scaffolds mimicking skin extracellular matrix for enhanced wound healing, new findings confirm the viscoelastic behaviour of the inter-lamellar matrix of the disc annulus fibrosus in radial and circumferential directions of loading, 3d printed, controlled release, tritherapeutic tablet matrix for advanced anti-hiv-1 drug delivery, computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model, pressure-induced end-plate fracture in the porcine spine: is the annulus fibrosus susceptible to damage?, dual electrospun supramolecular polymer systems for selective cell migration, regional mechanical and biochemical properties of the porcine cortical meninges, new insights into the viscoelastic and failure mechanical properties of the elastic fiber network of the inter-lamellar matrix in the annulus fibrosus of the disc, initial scaffold thickness affects the emergence of a geometrical and mechanical equilibrium in engineered cardiovascular tissues, development of an improved parameter fitting method for planar biaxial testing using rakes, the biomechanics of the inter-lamellar matrix and the lamellae during progression to lumbar disc herniation: which is the weakest structure?, mechanically robust cryogels with injectability and bioprinting supportability for adipose tissue engineering, biomechanical characterization of human dura mater, 3d printed, pva–paa hydrogel loaded-polycaprolactone scaffold for the delivery of hydrophilic in-situ formed sodium indomethacin, a transverse isotropic constitutive model for the aortic valve tissue incorporating rate-dependency and fibre dispersion: application to biaxial deformation, decoupling the effect of shear stress and stretch on tissue growth and remodeling in a vascular graft, an investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves, biaxial mechanical data of porcine atrioventricular valve leaflets, biaxial mechanical characterization of atrioventricular heart valves, biaxial experimental and analytical characterization of a dielectric elastomer, biaxial mechanical properties of bovine jugular venous valve leaflet tissues, comparison of femoropopliteal artery stents under axial and radial compression, axial tension, bending, and torsion deformations, constitutive modeling of human femoropopliteal artery biaxial stiffening due to aging and diabetes, constitutive modeling of jugular vein-derived venous valve leaflet tissues, design and characterization of a hyperelastic tubular soft composite, in situ heart valve tissue engineering using a bioresorbable elastomeric implant – from material design to 12 months follow-up in sheep, jetvalve: rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement, limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery, mechanically robust electrospun hydrogel scaffolds crosslinked via supramolecular interactions, nondestructive mechanical characterization of developing biological tissues using inflation testing, on the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture, paraspinal muscle passive stiffness remodels in direct response to spine stiffness: a study using the ent1-deficient mouse, tensile behaviour of individual fibre bundles in the human lumbar anulus fibrosus, urinary bladder versus gastrointestinal tissue: a comparative study of their biomechanical properties for urinary tract reconstruction, a comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosis tensile properties, acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro, age-dependent changes in geometry, tissue composition and mechanical properties of fetal to adult cryopreserved human heart valves, are adipose-derived stem cells cultivated in human platelet lysate suitable for heart valve tissue engineering, biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region, biomechanical characterization of ascending aortic aneurysms, biomechanical properties and microstructure of heart chambers: a paired comparison study in an ovine model, characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis, constitutive description of human femoropopliteal artery aging, deposition of a hydrophilic nanocomposite-based coating on a silicone hydrogel through a laser process to minimize uv exposure and bacterial contamination, improved geometry of decellularized tissue engineered heart valves to prevent leaflet retraction, inflation and bi-axial tensile testing of healthy porcine carotid arteries, modulation of collaen fiber orientation by strain-controlled enzymatic degradation, nanocomposited coatings produced by laser-assisted process to prevent silicone hydrogels from protein fouling and bacterial contamination, patient specific vascular benchtop models for development and validation of medical devices for minimally invasive procedures, peak stress in the annulus fibrosis under cyclic biaxial tensile loading, phototactic guidance of a tissue-engineered soft-robotic ray, planar biaxial testing of heart valve cusp replacement biomaterials: experiments, theory and material constants, planar biaxial testing of soft biological tissue using rakes: a critical analysis of protocol and fitting process, production of synthetic, para-aramid and biopolymer nanofibers by immersion rotary jet-spinning, quantification of coupled stiffness and fiber orientation remodeling in hypertensive rat right-ventricular myocardium using 3d ultrasound speckle tracking with biaxial testing, the aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae, the choice of a constitutive formulation for modeling limb flexion-induced deformations and stresses in the human femoropopliteal arteries of different ages, the effect of local hydration environment on the mechanical properties and unloaded temporal changes of isolated porcine annular samples, adipose derived tissue engineered heart valve, biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: effects of collagenase concentration and equibiaxial strain state, building a better infarct: modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction, corneal collagen cross-linking combined with simulation of femtosecond laser-assisted refractive lens extraction: an ex vivo biomechanical effect evaluation, development of non-cell adhesive vascular grafts using supramolecular building blocks, high-irradiance cxl combined with myopic lasik: flap and residual stroma biomechanical properties studied ex-vivo, leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion, methods for using 3-d ultrasound speckle tracking in biaxial mechanical testing of biological tissue samples, nanocomposite silicone hydrogels with a laser-assisted surface modification for inhibiting the growth of baterial biofilm, regional and depth variability of porcine meniscal mechanical properties through biaxial testing, superior tissue evolution in slow degrading scaffolds for valvular tissue engineering, the biomechanics of eyelid tarsus tissue, cardiac function of the naked mole-rat: echophysiological responses to working underground, directional biomechanical properties of porcine skin tissue, modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues, should a native depth-dependent distribution of human meniscus constitutive components be considered in fea-models of the knee joint?, strain-dependent modulation of macrophage polarization within scaffolds, structural and mechanical adaptations of right ventrical free wall myocardium to pressure overload, the biaxial biomechanical behavior of adominal aortic aneurysm tissue, the biaxial mechanical behaviour of abdominal aortic aneurysm intraluminal thrombus: classification of morphology and the determination of layer and region specific properties, the impact of long term freezing on the mechanical properties of porcine aortic tissue, vascular elastography: a validation study, a nanocomposite contact lens for the delivery of hydrophilic protein drugs, comparison of methods used to measure the thickness of soft tissues and their influence on the evaluation of tensile stress, corneal resistance to shear force after uva-riboflavin cross-linking, in vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells, mechanical analysis of ovine and pediatric pulmonary artery for heart valve stent design, mechanics of the pulmonary valve in the aortic position, reduction of stromal swelling pressure after uva-riboflavin cross-linking, a murine experimental model for the mechanical behavior of viable right-ventricular myocardium, an examination of the mechanical properties of the annulus fibrosus: the effect of vibration on the intra-lamellar matrix strength, application of simple biomechanical and biochemical tests to heart valve leaflets: implications for heart valve characterization and tissue engineering, biomechanical properties of the transverse carpal ligament under biaxial strain, multi-scale mechanical characterization of scaffolds for heart valve tissue engineering, a comparison of uniaxial and biaxial mechanical properties of the annulus fibrosus: a porcine model, does vibration influence the initiation of intervertebral disc herniation, novel lap test determines the mechanics of delamination between annular lamellae of the intervertebral disc, surfactant assisted incorporation of single-walled carbon nanotubes into a chitosan-polyvinylpyrrolidone polymer, an examination of the influence of strain rate on subfailure mechanical properties of the annulus fibrosus, biaxial mechanical testing of human sclera, effects of sclera stiffness on biomechanics of the optic nerve head in glaucoma, effects of sclera stiffness properties on optic nerve head biomechanics, fabrication of nanofiber reinforced protein structures for tissue engineering, strain uniformity in biaxial specimens is highly sensitive to attachment details, the influence of the tensile material properties of single annulus fibrosus lamellae and the interlamellar matrix strength on disc herniation and progression, functional arrays of human pluripotent stem cell-derived cardiac microtissues,a	cellscale	李先生
BioTester	an investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets, strain effects on collagen proteolysis in heart valve tissues, comparison of biomechanical properties and microstructure of trabeculae carneae, papillary muscles, and myocardium in the human heart, rate-dependency of the mechanical behavior of semilunar heart valves under biaxial deformation, an investigation of layer-specific tissue biomechanics of porcine atrioventricular valve anterior leaflets, the degradation and performance of electrospun supramolecular vascular scaffolds examined upon in vitro enzymatic exposure, mechanical damage characterization in human femoropopliteal arteries of different ages, cyclic strain affects macrophage cytokine secretion and extracellular matrix turnover in electrospun scaffolds, image-based analysis of uniaxial ring test for mechanical characterization of soft materials and biological tissues, mechanical properties of autologous pericardium change with fixation time: implications for valve reconstruction, tissue level mechanical properties and extracellular matrix investigation of the bovine jugular venous valve tissue, regional biaxial mechanical data of the mitral and tricuspid valve anterior leaflets, mechanics of the tricuspid valve-from clinical diagnosis/treatment, in-vivo and in-vitro investigations, to patient-specific biomechanical modeling., an investigation of the glycosaminoglycan contribution to biaxial mechanical behaviours of porcine atrioventricular heart valve leaflets, macrophage-driven biomaterial degradation depends on scaffold microarchitecture, the effect of axial torsion on the mechanical properties of the annulus fibrosus, integration of polarized spatial frequency domain imaging (psfdi) with a biaxial mechanical testing system for dynamic quantification of collagen architecture in soft collagenous tissues, an integrated opto-mechanical system for quantification of dynamic microstructure and mechanics of heart valve tissues, effects of longitudinal pre-stretch on the mechanics of human aorta before and after thoracic endovascular aortic repair (tevar) in trauma patients, human in vitro model of material-driven vascular regeneration reveals how cyclic stretch and shear stress differentially modulate inflammation and tissue formation, some effects of different constitutive laws on fsi simulation for the mitral valve, biomechanical restoration potential of pentagalloyl glucose after arterial extracellular matrix degeneration, an investigation of the effect of freezing storage on the biaxial mechanical properties of excised porcine tricuspid valve anterior leaflets, a detailed mechanical and microstructural analysis of the ovine tricuspid valve leaflets, the regional-dependent biaxial behavior of young and aged mouse skin: a detailed histomechanical characterization, residual strain analysis, and constitutive model, biaxial mechanical behavior of bovine saphenous venous valve leaflets, prevalence of calcification in human femoropopliteal arteries and its association with demographics, risk factors, and arterial stiffness, comparison of corneal biomechanics after myopic small-incision lenticule extraction compared to lasik: an ex vivo study, dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: case report and failure analysis, puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization, biomechanical evaluation of a personalized external aortic root support applied in the ross procedure, polydopamine as sizing on carbon fiber surfaces for enhancement of epoxy laminated composites, comparison of in vivo vs. ex situ obtained material properties of sheep common carotid artery, soy protein/cellulose nanofiber scaffolds mimicking skin extracellular matrix for enhanced wound healing, new findings confirm the viscoelastic behaviour of the inter-lamellar matrix of the disc annulus fibrosus in radial and circumferential directions of loading, 3d printed, controlled release, tritherapeutic tablet matrix for advanced anti-hiv-1 drug delivery, computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model, pressure-induced end-plate fracture in the porcine spine: is the annulus fibrosus susceptible to damage?, dual electrospun supramolecular polymer systems for selective cell migration, regional mechanical and biochemical properties of the porcine cortical meninges, new insights into the viscoelastic and failure mechanical properties of the elastic fiber network of the inter-lamellar matrix in the annulus fibrosus of the disc, initial scaffold thickness affects the emergence of a geometrical and mechanical equilibrium in engineered cardiovascular tissues, development of an improved parameter fitting method for planar biaxial testing using rakes, the biomechanics of the inter-lamellar matrix and the lamellae during progression to lumbar disc herniation: which is the weakest structure?, mechanically robust cryogels with injectability and bioprinting supportability for adipose tissue engineering, biomechanical characterization of human dura mater, 3d printed, pva–paa hydrogel loaded-polycaprolactone scaffold for the delivery of hydrophilic in-situ formed sodium indomethacin, a transverse isotropic constitutive model for the aortic valve tissue incorporating rate-dependency and fibre dispersion: application to biaxial deformation, decoupling the effect of shear stress and stretch on tissue growth and remodeling in a vascular graft, an investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves, biaxial mechanical data of porcine atrioventricular valve leaflets, biaxial mechanical characterization of atrioventricular heart valves, biaxial experimental and analytical characterization of a dielectric elastomer, biaxial mechanical properties of bovine jugular venous valve leaflet tissues, comparison of femoropopliteal artery stents under axial and radial compression, axial tension, bending, and torsion deformations, constitutive modeling of human femoropopliteal artery biaxial stiffening due to aging and diabetes, constitutive modeling of jugular vein-derived venous valve leaflet tissues, design and characterization of a hyperelastic tubular soft composite, in situ heart valve tissue engineering using a bioresorbable elastomeric implant – from material design to 12 months follow-up in sheep, jetvalve: rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement, limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery, mechanically robust electrospun hydrogel scaffolds crosslinked via supramolecular interactions, nondestructive mechanical characterization of developing biological tissues using inflation testing, on the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture, paraspinal muscle passive stiffness remodels in direct response to spine stiffness: a study using the ent1-deficient mouse, tensile behaviour of individual fibre bundles in the human lumbar anulus fibrosus, urinary bladder versus gastrointestinal tissue: a comparative study of their biomechanical properties for urinary tract reconstruction, a comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosis tensile properties, acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro, age-dependent changes in geometry, tissue composition and mechanical properties of fetal to adult cryopreserved human heart valves, are adipose-derived stem cells cultivated in human platelet lysate suitable for heart valve tissue engineering, biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region, biomechanical characterization of ascending aortic aneurysms, biomechanical properties and microstructure of heart chambers: a paired comparison study in an ovine model, characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis, constitutive description of human femoropopliteal artery aging, deposition of a hydrophilic nanocomposite-based coating on a silicone hydrogel through a laser process to minimize uv exposure and bacterial contamination, improved geometry of decellularized tissue engineered heart valves to prevent leaflet retraction, inflation and bi-axial tensile testing of healthy porcine carotid arteries, modulation of collaen fiber orientation by strain-controlled enzymatic degradation, nanocomposited coatings produced by laser-assisted process to prevent silicone hydrogels from protein fouling and bacterial contamination, patient specific vascular benchtop models for development and validation of medical devices for minimally invasive procedures, peak stress in the annulus fibrosis under cyclic biaxial tensile loading, phototactic guidance of a tissue-engineered soft-robotic ray, planar biaxial testing of heart valve cusp replacement biomaterials: experiments, theory and material constants, planar biaxial testing of soft biological tissue using rakes: a critical analysis of protocol and fitting process, production of synthetic, para-aramid and biopolymer nanofibers by immersion rotary jet-spinning, quantification of coupled stiffness and fiber orientation remodeling in hypertensive rat right-ventricular myocardium using 3d ultrasound speckle tracking with biaxial testing, the aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae, the choice of a constitutive formulation for modeling limb flexion-induced deformations and stresses in the human femoropopliteal arteries of different ages, the effect of local hydration environment on the mechanical properties and unloaded temporal changes of isolated porcine annular samples, adipose derived tissue engineered heart valve, biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: effects of collagenase concentration and equibiaxial strain state, building a better infarct: modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction, corneal collagen cross-linking combined with simulation of femtosecond laser-assisted refractive lens extraction: an ex vivo biomechanical effect evaluation, development of non-cell adhesive vascular grafts using supramolecular building blocks, high-irradiance cxl combined with myopic lasik: flap and residual stroma biomechanical properties studied ex-vivo, leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion, methods for using 3-d ultrasound speckle tracking in biaxial mechanical testing of biological tissue samples, nanocomposite silicone hydrogels with a laser-assisted surface modification for inhibiting the growth of baterial biofilm, regional and depth variability of porcine meniscal mechanical properties through biaxial testing, superior tissue evolution in slow degrading scaffolds for valvular tissue engineering, the biomechanics of eyelid tarsus tissue, cardiac function of the naked mole-rat: echophysiological responses to working underground, directional biomechanical properties of porcine skin tissue, modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues, should a native depth-dependent distribution of human meniscus constitutive components be considered in fea-models of the knee joint?, strain-dependent modulation of macrophage polarization within scaffolds, structural and mechanical adaptations of right ventrical free wall myocardium to pressure overload, the biaxial biomechanical behavior of adominal aortic aneurysm tissue, the biaxial mechanical behaviour of abdominal aortic aneurysm intraluminal thrombus: classification of morphology and the determination of layer and region specific properties, the impact of long term freezing on the mechanical properties of porcine aortic tissue, vascular elastography: a validation study, a nanocomposite contact lens for the delivery of hydrophilic protein drugs, comparison of methods used to measure the thickness of soft tissues and their influence on the evaluation of tensile stress, corneal resistance to shear force after uva-riboflavin cross-linking, in vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells, mechanical analysis of ovine and pediatric pulmonary artery for heart valve stent design, mechanics of the pulmonary valve in the aortic position, reduction of stromal swelling pressure after uva-riboflavin cross-linking, a murine experimental model for the mechanical behavior of viable right-ventricular myocardium, an examination of the mechanical properties of the annulus fibrosus: the effect of vibration on the intra-lamellar matrix strength, application of simple biomechanical and biochemical tests to heart valve leaflets: implications for heart valve characterization and tissue engineering, biomechanical properties of the transverse carpal ligament under biaxial strain, multi-scale mechanical characterization of scaffolds for heart valve tissue engineering, a comparison of uniaxial and biaxial mechanical properties of the annulus fibrosus: a porcine model, does vibration influence the initiation of intervertebral disc herniation, novel lap test determines the mechanics of delamination between annular lamellae of the intervertebral disc, surfactant assisted incorporation of single-walled carbon nanotubes into a chitosan-polyvinylpyrrolidone polymer, an examination of the influence of strain rate on subfailure mechanical properties of the annulus fibrosus, biaxial mechanical testing of human sclera, effects of sclera stiffness on biomechanics of the optic nerve head in glaucoma, effects of sclera stiffness properties on optic nerve head biomechanics, fabrication of nanofiber reinforced protein structures for tissue engineering, strain uniformity in biaxial specimens is highly sensitive to attachment details, the influence of the tensile material properties of single annulus fibrosus lamellae and the interlamellar matrix strength on disc herniation and progression, functional arrays of human pluripotent stem cell-derived cardiac microtissues,a	cellscale	李先生
BioTester	an investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets, strain effects on collagen proteolysis in heart valve tissues, comparison of biomechanical properties and microstructure of trabeculae carneae, papillary muscles, and myocardium in the human heart, rate-dependency of the mechanical behavior of semilunar heart valves under biaxial deformation, an investigation of layer-specific tissue biomechanics of porcine atrioventricular valve anterior leaflets, the degradation and performance of electrospun supramolecular vascular scaffolds examined upon in vitro enzymatic exposure, mechanical damage characterization in human femoropopliteal arteries of different ages, cyclic strain affects macrophage cytokine secretion and extracellular matrix turnover in electrospun scaffolds, image-based analysis of uniaxial ring test for mechanical characterization of soft materials and biological tissues, mechanical properties of autologous pericardium change with fixation time: implications for valve reconstruction, tissue level mechanical properties and extracellular matrix investigation of the bovine jugular venous valve tissue, regional biaxial mechanical data of the mitral and tricuspid valve anterior leaflets, mechanics of the tricuspid valve-from clinical diagnosis/treatment, in-vivo and in-vitro investigations, to patient-specific biomechanical modeling., an investigation of the glycosaminoglycan contribution to biaxial mechanical behaviours of porcine atrioventricular heart valve leaflets, macrophage-driven biomaterial degradation depends on scaffold microarchitecture, the effect of axial torsion on the mechanical properties of the annulus fibrosus, integration of polarized spatial frequency domain imaging (psfdi) with a biaxial mechanical testing system for dynamic quantification of collagen architecture in soft collagenous tissues, an integrated opto-mechanical system for quantification of dynamic microstructure and mechanics of heart valve tissues, effects of longitudinal pre-stretch on the mechanics of human aorta before and after thoracic endovascular aortic repair (tevar) in trauma patients, human in vitro model of material-driven vascular regeneration reveals how cyclic stretch and shear stress differentially modulate inflammation and tissue formation, some effects of different constitutive laws on fsi simulation for the mitral valve, biomechanical restoration potential of pentagalloyl glucose after arterial extracellular matrix degeneration, an investigation of the effect of freezing storage on the biaxial mechanical properties of excised porcine tricuspid valve anterior leaflets, a detailed mechanical and microstructural analysis of the ovine tricuspid valve leaflets, the regional-dependent biaxial behavior of young and aged mouse skin: a detailed histomechanical characterization, residual strain analysis, and constitutive model, biaxial mechanical behavior of bovine saphenous venous valve leaflets, prevalence of calcification in human femoropopliteal arteries and its association with demographics, risk factors, and arterial stiffness, comparison of corneal biomechanics after myopic small-incision lenticule extraction compared to lasik: an ex vivo study, dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: case report and failure analysis, puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization, biomechanical evaluation of a personalized external aortic root support applied in the ross procedure, polydopamine as sizing on carbon fiber surfaces for enhancement of epoxy laminated composites, comparison of in vivo vs. ex situ obtained material properties of sheep common carotid artery, soy protein/cellulose nanofiber scaffolds mimicking skin extracellular matrix for enhanced wound healing, new findings confirm the viscoelastic behaviour of the inter-lamellar matrix of the disc annulus fibrosus in radial and circumferential directions of loading, 3d printed, controlled release, tritherapeutic tablet matrix for advanced anti-hiv-1 drug delivery, computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model, pressure-induced end-plate fracture in the porcine spine: is the annulus fibrosus susceptible to damage?, dual electrospun supramolecular polymer systems for selective cell migration, regional mechanical and biochemical properties of the porcine cortical meninges, new insights into the viscoelastic and failure mechanical properties of the elastic fiber network of the inter-lamellar matrix in the annulus fibrosus of the disc, initial scaffold thickness affects the emergence of a geometrical and mechanical equilibrium in engineered cardiovascular tissues, development of an improved parameter fitting method for planar biaxial testing using rakes, the biomechanics of the inter-lamellar matrix and the lamellae during progression to lumbar disc herniation: which is the weakest structure?, mechanically robust cryogels with injectability and bioprinting supportability for adipose tissue engineering, biomechanical characterization of human dura mater, 3d printed, pva–paa hydrogel loaded-polycaprolactone scaffold for the delivery of hydrophilic in-situ formed sodium indomethacin, a transverse isotropic constitutive model for the aortic valve tissue incorporating rate-dependency and fibre dispersion: application to biaxial deformation, decoupling the effect of shear stress and stretch on tissue growth and remodeling in a vascular graft, an investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves, biaxial mechanical data of porcine atrioventricular valve leaflets, biaxial mechanical characterization of atrioventricular heart valves, biaxial experimental and analytical characterization of a dielectric elastomer, biaxial mechanical properties of bovine jugular venous valve leaflet tissues, comparison of femoropopliteal artery stents under axial and radial compression, axial tension, bending, and torsion deformations, constitutive modeling of human femoropopliteal artery biaxial stiffening due to aging and diabetes, constitutive modeling of jugular vein-derived venous valve leaflet tissues, design and characterization of a hyperelastic tubular soft composite, in situ heart valve tissue engineering using a bioresorbable elastomeric implant – from material design to 12 months follow-up in sheep, jetvalve: rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement, limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery, mechanically robust electrospun hydrogel scaffolds crosslinked via supramolecular interactions, nondestructive mechanical characterization of developing biological tissues using inflation testing, on the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture, paraspinal muscle passive stiffness remodels in direct response to spine stiffness: a study using the ent1-deficient mouse, tensile behaviour of individual fibre bundles in the human lumbar anulus fibrosus, urinary bladder versus gastrointestinal tissue: a comparative study of their biomechanical properties for urinary tract reconstruction, a comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosis tensile properties, acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro, age-dependent changes in geometry, tissue composition and mechanical properties of fetal to adult cryopreserved human heart valves, are adipose-derived stem cells cultivated in human platelet lysate suitable for heart valve tissue engineering, biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region, biomechanical characterization of ascending aortic aneurysms, biomechanical properties and microstructure of heart chambers: a paired comparison study in an ovine model, characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis, constitutive description of human femoropopliteal artery aging, deposition of a hydrophilic nanocomposite-based coating on a silicone hydrogel through a laser process to minimize uv exposure and bacterial contamination, improved geometry of decellularized tissue engineered heart valves to prevent leaflet retraction, inflation and bi-axial tensile testing of healthy porcine carotid arteries, modulation of collaen fiber orientation by strain-controlled enzymatic degradation, nanocomposited coatings produced by laser-assisted process to prevent silicone hydrogels from protein fouling and bacterial contamination, patient specific vascular benchtop models for development and validation of medical devices for minimally invasive procedures, peak stress in the annulus fibrosis under cyclic biaxial tensile loading, phototactic guidance of a tissue-engineered soft-robotic ray, planar biaxial testing of heart valve cusp replacement biomaterials: experiments, theory and material constants, planar biaxial testing of soft biological tissue using rakes: a critical analysis of protocol and fitting process, production of synthetic, para-aramid and biopolymer nanofibers by immersion rotary jet-spinning, quantification of coupled stiffness and fiber orientation remodeling in hypertensive rat right-ventricular myocardium using 3d ultrasound speckle tracking with biaxial testing, the aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae, the choice of a constitutive formulation for modeling limb flexion-induced deformations and stresses in the human femoropopliteal arteries of different ages, the effect of local hydration environment on the mechanical properties and unloaded temporal changes of isolated porcine annular samples, adipose derived tissue engineered heart valve, biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: effects of collagenase concentration and equibiaxial strain state, building a better infarct: modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction, corneal collagen cross-linking combined with simulation of femtosecond laser-assisted refractive lens extraction: an ex vivo biomechanical effect evaluation, development of non-cell adhesive vascular grafts using supramolecular building blocks, high-irradiance cxl combined with myopic lasik: flap and residual stroma biomechanical properties studied ex-vivo, leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion, methods for using 3-d ultrasound speckle tracking in biaxial mechanical testing of biological tissue samples, nanocomposite silicone hydrogels with a laser-assisted surface modification for inhibiting the growth of baterial biofilm, regional and depth variability of porcine meniscal mechanical properties through biaxial testing, superior tissue evolution in slow degrading scaffolds for valvular tissue engineering, the biomechanics of eyelid tarsus tissue, cardiac function of the naked mole-rat: echophysiological responses to working underground, directional biomechanical properties of porcine skin tissue, modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues, should a native depth-dependent distribution of human meniscus constitutive components be considered in fea-models of the knee joint?, strain-dependent modulation of macrophage polarization within scaffolds, structural and mechanical adaptations of right ventrical free wall myocardium to pressure overload, the biaxial biomechanical behavior of adominal aortic aneurysm tissue, the biaxial mechanical behaviour of abdominal aortic aneurysm intraluminal thrombus: classification of morphology and the determination of layer and region specific properties, the impact of long term freezing on the mechanical properties of porcine aortic tissue, vascular elastography: a validation study, a nanocomposite contact lens for the delivery of hydrophilic protein drugs, comparison of methods used to measure the thickness of soft tissues and their influence on the evaluation of tensile stress, corneal resistance to shear force after uva-riboflavin cross-linking, in vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells, mechanical analysis of ovine and pediatric pulmonary artery for heart valve stent design, mechanics of the pulmonary valve in the aortic position, reduction of stromal swelling pressure after uva-riboflavin cross-linking, a murine experimental model for the mechanical behavior of viable right-ventricular myocardium, an examination of the mechanical properties of the annulus fibrosus: the effect of vibration on the intra-lamellar matrix strength, application of simple biomechanical and biochemical tests to heart valve leaflets: implications for heart valve characterization and tissue engineering, biomechanical properties of the transverse carpal ligament under biaxial strain, multi-scale mechanical characterization of scaffolds for heart valve tissue engineering, a comparison of uniaxial and biaxial mechanical properties of the annulus fibrosus: a porcine model, does vibration influence the initiation of intervertebral disc herniation, novel lap test determines the mechanics of delamination between annular lamellae of the intervertebral disc, surfactant assisted incorporation of single-walled carbon nanotubes into a chitosan-polyvinylpyrrolidone polymer, an examination of the influence of strain rate on subfailure mechanical properties of the annulus fibrosus, biaxial mechanical testing of human sclera, effects of sclera stiffness on biomechanics of the optic nerve head in glaucoma, effects of sclera stiffness properties on optic nerve head biomechanics, fabrication of nanofiber reinforced protein structures for tissue engineering, strain uniformity in biaxial specimens is highly sensitive to attachment details, the influence of the tensile material properties of single annulus fibrosus lamellae and the interlamellar matrix strength on disc herniation and progression, functional arrays of human pluripotent stem cell-derived cardiac microtissues,a	cellscale	李先生
	multi-modal characterization of polymeric gels to determine the influence of testing method on observed elastic modulus david m. kingsley, caitlin h.mccleery, christopher d.l.johnson, michael t.k.bramson, deniz rende, ryan j.gilbert, david t.corr journal of the mechanical behavior of biomedical materials, available online 10 january 2019, https://doi.org/10.1016/j.jmbbm.2019.01.003 demand for materials that mechanically replicate native tissue has driven development and characterization of various new biomaterials. however, a consequence of materials and characterization technique diversity is a lack of consensus within the... read more https://www.sciencedirect.com/science/article/pii/s1751616118308518#f0015 cross-linked cellulose nanocrystal aerogels as viable bone tissue scaffolds daniel a. osorioa, bryan e.j. lee, jacek m. kwiecien, xiaoyue wang, iflah shahid, ariana l. hurley, emily d. cranston, kathryn grandfield acta biomaterialia, 2019, https://doi.org/10.1016/j.actbio.2019.01.049 chemically cross-linked cellulose nanocrystal (cnc) aerogels possess many properties beneficial for bone tissue scaffolding applications. cncs were extracted using sulfuric acid or phosphoric acid, to produce cncs with sulfate and phosphate... read more https://www.sciencedirect.com/science/article/pii/s1742706119300716 viscoelasticity and histology of the human cartilage in healthy and degenerated conditions of the knee michael seidenstuecker, julius watrinet , anke bernstein, norbert p. suedkamp , sergio h. latorre anastasija maks and hermann o. mayr journal of orthopaedic surgery and research, november 2019, 14:256. doi: 10.1186/s13018-019-1308-5 background: there are many studies on osteoarthritis, but only a few studies deal with human arthrosis, comparing the mechanical properties of healthy and diseased samples. in most of these studies, only isolated areas of the tibia are... read more https://www.researchgate.net/publication/335156117_viscoelasticity_and_histology_of_the_human_cartilage_in_healthy_and_degenerated_conditions_of_the_knee high impact exercise improves bone microstructure and strength in growing rats m. tanvir, i. londono, f. moldovan and i. villemure nature scientific reports, volume 9, article number: 13128 (2019) https://doi.org/10.1038/s41598-019-49432-2 physical activity is beneficial for skeletal development. however, impact sports during adolescence, leading to bone growth retardation and/or bone quality improvement, remains unexplained. this study investigated the effects of in vivo low... read more https://www.nature.com/articles/s41598-019-49432-2 a study of saliva lubrication using a compliant oral mimic g. carpenter, s. bozorgi, s. vladescu, a.e. forte, c. myant, r.v. potineni, t. reddyhoff, and s.k. baier food hydrocolloids, elsevier, available online 23 january 2019, https://doi.org/10.1016/j.foodhyd.2019.01.049 due to ethical issues and the difficulty in obtaining biological tissues, it is important to find synthetic elastomers that can be used as replacement test media for research purposes. an important example of this is friction testing to... read more https://www.sciencedirect.com/science/article/pii/s0268005x1831885x experimental and finite element analyses of bone strains in the growing rat tibia induced by in vivo axial compression tanvir mustafy, irène londono, isabelle villemure journal of the mechanical behavior of biomedical materials the objective of this study was to develop and validate a voxel based fe modeling approach to investigate bone strains from in vivo rat tibial compression during the adolescent period. to do so, in vivo strain gauge measurements and voxel based... read more https://doi.org/10.1016/j.jmbbm.2019.03.009 properties of biopolymer films in ionic solutions and their applications as 3d printed personalized wound dressings d.p. ramos university of toronto (canada), proquest dissertations publishing, 2019. 13805509. this thesis describes the effects of ionic solutions on biopolymer films and the development of a 3d printed personalized wound dressing. chitosan, gelatin, and composite chitosan/gelatin films were exposed to nacl, na2so4, and cacl2... read more https://search.proquest.com/openview/1e26de46c42e25c0898d7b9ab138b6c7/1?pq-origsite=gscholar&cbl=18750&diss=y quantifying vocal fold wound?healing biomechanical property changes g. r. dion, t. guda, s. mukudai, r.bing, j-f. lavoie and r.c. branski laryngoscope. 2019 may 6. doi: 10.1002/lary.27999 objectives development of novel vocal fold (vf) therapeutics is limited by a lack of standardized, meaningful outcomes. we hypothesize that automated microindentation?based vf biomechanical property mapping matched to histology... read more https://www.ncbi.nlm.nih.gov/pubmed/31059589 compressive mechanical properties of porcine brain: experimentation and modeling of the tissue hydration effects r.k. prabhu, m.t. begonia, w.r. whittington, m.a. murphy, y. mao, j. liao, l.n. williams, m.f. horstemeyer and j. sheng bioengineering 2019, 6, 40; doi:10.3390/bioengineering6020040 abstract: designing protective systems for the human head—and, hence, the brain—requires understanding the brain's microstructural response to mechanical insults. we present the behavior of wet and dry porcine brain undergoing... read more https://www.ncbi.nlm.nih.gov/pubmed/31067801 injectable poly(oligoethylene glycol methacrylate)-based hydrogels fabricated from highly branched precursor polymers: controlling gel properties by precursor polymer morphology ivan urosev, helen dorrington, nicola muzzin, richard alsop, emilia bakaic, trevor gilbert, maikel rheinstädter and todd hoare acs applied polymer materials, 2019, 1, 3, 369-380 january 24, 2019 https://doi.org/10.1021/acsapm.8b00085 the physicochemical properties of injectable hydrogels are typically modified by altering the chemistry of the precursor polymer and/or the amount or type of cross-linker, both of which can lead to hydrogels with altered mechanics, swelling,... read more https://pubs.acs.org/doi/10.1021/acsapm.8b00085 intervertebral disc implant r kandel, jp santerre, sq li us patent app. 10195044, 2019 the present inventors have generated the tissues that comprise the intervertebral disc and have established viable protocols and tissue conditions that facilitate integration of all the tissue components into one functional tissue so it can... read more https://patentimages.storage.googleapis.com/42/7a/ef/ff71221c3da781/us10195044.pdf comparative study on complexes formed by chitosan and different polyanions: potential of chitosan-pectin biomaterials as scaffolds in tissue engineering fernanda carla bombaldi de souza, renata francielle bombaldi de souza, bernard drouin, diego mantovani and angela maria moraes international journal of biological macromolecules, volume 132, 1 july 2019, pages 178-189 polyelectrolyte complexes of chitosan (ch) and pectin (pc) or alginate (alg) were produced in the presence or absence of the silicone gel silpuran® 2130 a/b (sil) and the surfactant kolliphor® p188 (kol). ch-pc-kol-based formulations presented... read more https://www.sciencedirect.com/science/article/pii/s0141813019308141 on-demand radial electrodeposition of alginate tubular structures d. m. kingsley, j. a. capuano and d. t. corr acs biomater. sci. eng. publication date:june 12, 2019, https://doi.org/10.1021/acsbiomaterials.9b00415 we present an electrodeposition technique for fabricating tubular alginate structures. in this technique, two electrodes (anode and cathode) are suspended in a solution of alginate and insoluble calcium carbonate particles, and the application of... read more https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.9b00415 osteochondral repair and electromechanical evaluation of custom 3d scaffold microstructured by direct laser writing lithography j. maciulaitis, m. miskiniene, s. rekstyte, m.bratchikov, a. darinskas, a.simbelyte, g. daunoras, a. laurinaviciene, a. laurinavicius, r. gudas, m. malinauskas and r. maciulaitis cartilage · may 2019, https://doi.org/10.1177/1947603519847745 objective the objective of this study was to assess a novel 3d microstructured scaffold seeded with allogeneic chondrocytes (cells) in a rabbit osteochondral defect model. design direct laser writing lithography in... read more https://journals.sagepub.com/doi/abs/10.1177/1947603519847745?journalcode=cara magnesium phosphate hydrogels f tamimi marino, a ali al-hashedi, m laurenti, a ebraheem al subaie, m-n abdallah, i tamimi marino https://patents.google.com/patent/us20190002282a1/en the present invention relates to magnesium phosphate hydrogels. more specifically, the present invention is concerned with such gels and their uses as scaffolds for bone tissue engineering, as drug delivery systems and in pastes for cleaning dental... read more https://patents.google.com/patent/us20190002282a1/en injectable poly(oligoethylene glycol methacrylate)-based hydrogels fabricated from highly branched precursor polymers: controlling gel properties by precursor polymer morphology i. urosev, h. dorrington, n. muzzin, r.j. alsop, e. bakaic, t. gilbert, m.c. rheinstadter, and t. hoare acs applied polymer materials just accepted manuscript, doi: 10.1021/acsapm.8b00085 the physicochemical properties of injectable hydrogels are typically modified by altering the chemistry of the precursor polymer and/or the... read more https://pubs.acs.org/doi/pdf/10.1021/acsapm.8b00085 bone-specific overexpression of pitx1 induces senile osteoporosis in mice through deficient self-renewal of mesenchymal progenitors and wnt pathway inhibition n. karam, j-f. lavoie, b. st-jacques, s. bouhanik, a. franco, n. ladoul and a. moreau scientific reports volume 9, article number: 3544 (2019) the cellular and molecular mechanisms underlying senile osteoporosisremain poorly understood. in this study, transgenic mcol1?1-pitx1 miceoverexpressing paired-like homeodomain 1 (pitx1), a homeobox transcriptionfactor, rapidly develop a severe... read more https://www.nature.com/articles/s41598-019-40274-6 go-modified flexible polymer nanocomposites fabricated via 3d stereolithography c.h.a. tsang, a. zhakeyev, d. y.c. leung and j. xuan front. chem. sci. eng. (2019). https://doi.org/10.1007/s11705-019-1836-x graphene oxide (go) induced enhancement of elastomer properties showed a great deal of potential in recent years, but it is still limited by the barrier of the complicated synthesis processes. stereolithography(sla),used in fabrication of... read more https://link.springer.com/article/10.1007/s11705-019-1836-x high-throughput synthesis, analysis, and optimization of injectable hydrogels for protein delivery fei xu, brandon corbett, sydney bell, chiyan zhang, monika budi hartono, zohreh jomeh farsangi, john f macgregor and todd hoare biomacromelecules 2019, publication date: november 5, 2019, https://doi.org/10.1021/acs.biomac.9b01132 the development of in situ-gelling hydrogels that can enable prolonged protein release is increasingly important due to the emergence of a growing number of protein-based therapeutics. herein, we describe a high-throughput strategy to fabricate,... read more https://pubs.acs.org/doi/abs/10.1021/acs.biomac.9b01132 simulation of acoustic propagation in 3d viscoelastic inhomogeneous media with application to medical shear wave elastography p. s. bidari, h. assi, r. s. c. cobbold, j. alirezaie and j. tavakkoli journal of theoretical and computational acoustics vol. 27, no. 03, 1950003 (2019) research papers, https://doi.org/10.1142/s2591728519500038 this paper proposes a new numerical framework to simulate ultrasound wave propagation in 3d viscoelastic heterogeneous media based on the elastodynamic wave equation including a 3d second-order time-domain perfectly matched layer formulation. a... read more https://www.worldscientific.com/doi/abs/10.1142/s2591728519500038 high-throughput synthesis and characterization of aryl silicones using the piers-rubinsztajn reaction a.f. schneider and m.a. brook chemistry–a european journal 09 october 2019 https://doi.org/10.1002/chem.201903658 arylsilicones are widely exploited for their thermal and optical properties. the creation of phenylsilicone elastomers with specific physical properties is typically done by a ‘one off' formulation and test process. we demonstrate that... read more https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201903658 synthetic presentation of noncanonical wnt5a motif promotes mechanosensing-dependent differentiation of stem cells and regeneration r. li, s. lin, m.zhu, y. deng, x. chen, k. wei, j. xu, g. li and l. bian sci adv 5, 10, eaaw 3896, doi: 10.1126/sciadv.aaw3896 noncanonical wnt signaling in stem cells is essential to numerous developmental events. however, no prior studies have capitalized on the osteoinductive potential of noncanonical wnt ligands to functionalize biomaterials in enhancing the... read more https://advances.sciencemag.org/content/advances/5/10/eaaw3896.full.pdf morphology and composition play distinct and complementary roles in the tolerance of plantar skin to mechanical load colin j. boyle, magdalena plotczyk, sergi fayos villalta, sharad patel, shehan hettiaratchy, spyros d. masouros, marc a. masen and claire a. higgins science advances, 09 oct 2019: vol. 5, no. 10, eaay0244, doi: 10.1126/sciadv.aay0244 plantar skin on the soles of the feet has a distinct morphology and composition that is thought to enhance its tolerance to mechanical loads, although the individual contributions of morphology and composition have never been quantified. here,... read more https://advances.sciencemag.org/content/5/10/eaay0244.full characterization of a novel decellularized bone marrow scaffold as an inductive environment for hematopoietic stem cells j.e. romero bianco, r. giardini rosa, a. congrains-castillo, p.p. joazeiro, s.d. waldman, j.f. weber, and s.t. olalla saad biomater. sci., 2019, advance article, first published on 19 jan 2019, doi 10.1039/c8bm01503a due to the increasing demand for a bone marrow study model, we developed a natural... read more https://pubs.rsc.org/en/content/articlelanding/2019/bm/c8bm01503a#!divabstract ultrashort time to echo magnetic resonance evaluation of calcium pyrophosphate crystal deposition in human menisci finkenstaedt t, biswas r, abeydeera na, siriwanarangsun p, healey r, statum s, bae wc and chung cb invest radiol. 2019 jun. 54(6):349-355. objectives: in human menisci, we aimed to investigate whether calcium pyrophosphate crystal deposition (cppd) affects biomechanical and quantitative mr properties, and their zonal distribution. read more https://www.ncbi.nlm.nih.gov/pubmed/30688685 moderate exercise prevents cartilage softening and muscle structural changes in a rat model of obesity j.l. rios, j.w. mather, j. michaiel, s.m. mattiello and w. herzog oarsi journal, april 2019 volume 27, supplement 1, page s155 purpose: osteoarthritis (oa) is a debilitating chronicdisease. currently, there is no cure or disease modifying treatment for oa.using a sprague-dawley rat model, it has been shown that ahigh-fat/high-sucrose (hfs) diet induced... read more https://www.oarsijournal.com/article/s1063-4584(19)30267-5/ppt development of a dispensing based additive manufacturing technique for the creation of alginate bone scatfolds j.j. varun ubc theses and dissertations, 2019. https://open.library.ubc.ca/circle/collections/ubctheses/24/items/1.0378434 bone scaffolds are used to treat large bone defects. there are noted advantages for moving away from the standard of using human bone to create these... read more https://open.library.ubc.ca/circle/collections/ubctheses/24/items/1.0378434 automated indentation of femoral and temporomandibular joints for characterization of cartilage tissue quality in fgf2 ko mice. tannin schmidt poster sat-996. american society for bone and mineral research, 21 sep 2019, orlando, florida, usa purpose: degenerative disorders affecting the mandibular condylar cartilage (mcc) of the temporomandibular joint (tmj), and the articular cartilage (ac) of the knee joint, are common chronic conditions. fibroblast growth factor 2 (fgf2) is a... read more https://www.asbmr.org/itinerarybuilder/presentationdetail.aspx?pid=b268f23b-6e58-4d3d-bea7-863d43c7f010&ptag=webitinerarysearch biomechanical characterization of tibial articular cartilage in hyp mice, a murine model of osteoarthritis in x-linked hypophosphatemia michael j. desimone, steven m. tommasini, christopher cape and carolyn m. macica poster sun-929. american society for bone and mineral research, 22 sep 2019, orlando, florida, usa the clinical picture of adult xlh is dominated by a pervasive, early-onset osteoarthritis (oa). using a murine xlh model, we have shown that the femoral/tibial joint of hyp mice lacks the mineralized zone of articular cartilage, a transitional tissue... read more https://www.asbmr.org/itinerarybuilder/presentationdetail.aspx?pid=6cc2af0d-9083-4d85-aeea-e0b063ca07af&ptag=webitinerarysearch a col1a2 mutation reveals bone fragility, hyperelasticity of skin and degeneration of articular cartilage in mice s. sim, a. blease, m. garon, e. quenneville and p. potter poster sun-053. american society for bone and mineral research, 22 sep 2019, orlando, florida, usa read more https://www.asbmr.org/itinerarybuilder/presentationdetail.aspx?pid=d998ad4c-3407-44f6-ac34-713e2a65b750&ptag=webitinerarysearch hierarchically structured, self-healing, fluorescent, bioactive hydrogels with self-organizing bundles of phage nanofilaments a. peivandi, l. tian, r. mahabir and z. hosseinidoust chem. mater. 201931155442-5449 publication date:july 24, 2019 https://doi.org/10.1021/acs.chemmater.9b00720 bacteriophages are essentially bionanoparticles with a protein coat, the composition of which can be controlled with atomic precision via genetic engineering, a property that makes them superior to synthetic nanoparticles as building blocks for... read more https://pubs.acs.org/doi/abs/10.1021/acs.chemmater.9b00720 development of an in vitro outer annulus fibrosus cartilage endplate model and its response to dynamic mechanical loading j. e. chong university of toronto tissue-engineering research to date has neglected to address the annulus fibrosus (af) cartilage endplate (cep) interface of the intervertebral disc. it was hypothesized that in vitro formed outer af and cartilage tissues will integrate... read more https://tspace.library.utoronto.ca/bitstream/1807/96075/3/chong_jasmine_e_201906_mas_thesis.pdf bottlebrush polymer compositions, lubricating fluid, porous materials comprising said compositions, and surface bearing said compositions x. banquy, j. faivre, b.r.shrestha, k. matyjaszewski, j.burdynska and f. moldovan us patent app. 16/095,051, 2019 a mixture of polymers with lubricating properties is provided. the polymer can be used to produce a lubricating fluid. they can also be born on a surface or embedded in a porous material. this mixture of polymers comprises (a) a pharmaceutically... read more https://patents.google.com/patent/us20190099521a1/en setting up a pre-clinical human model for mechanical induced osteoarthritis to investigate potential pharmacological agents e. houtman, m. van hoolwerff, r. coutinho de almeida, a. rodriguez ruiz, n. lakenberg, h.e. suchiman, m. tuerlings, r.g. timmermans, r.g. nelissen, y.f. ramos and i. meulenbelt osteoarthritis and cartilage, april 2019, volume 27, supplement 1, pages s80–s81. https://doi.org/10.1016/j.joca.2019.02.114 purpose: osteoarthritis (oa) is a joint disease characterized by cartilage degeneration and bone spur formation. due to the fact that there are no disease modifying drugs, oa is placing a high burden on society occurring during... read more https://www.oarsijournal.com/article/s1063-4584(19)30156-6/abstract cross-linked elastin-like polypeptide membranes as a model for medial arterial calcification o. gourgas, l. d. muiznieks, d. g.bello, a. nanci, s.sharpe and m. cerruti publication date:june 21, 2019 https://doi.org/10.1021/acs.biomac.9b00417 calcium phosphate minerals deposit on the elastin-rich medial layers of arteries in the majority of seniors, diabetic, and chronic kidney disease patients, causing severe cardiovascular complications. there is no cure for medial calcification, and... read more https://pubs.acs.org/doi/full/10.1021/acs.biomac.9b00417 the effect of in vivo chondrocyte depletion on the structural and functional properties of murine articular cartilage a.o. masson, j.m. corpuz, w.b. edwards and r.j. krawetz osteoarthritis and cartilage, april 2019, volume 27, supplement 1, page s80 articular cartilage is an intricate and remarkable tissue found within synovial joints. it is essential for providing low-friction and load bearing during movement, resulting in pain-free mobility. chondrocytes are the sole cell population present... read more https://www.oarsijournal.com/article/s1063-4584(19)30155-4/abstract a 3d bioprinted meniscus implant reinforced by chitosan/poly(vinyl alcohol) fibres e. kapyla, m. k. khan, s. pan, r. nickmanesh, s. beyer, j. ault, j. hwang, t. mohamed, and s. wadsworth 30th annual conference of the european society for biomaterials, ix-os31-01, #270, 12 september 2019, dresden, germany.
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